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KMID : 0604520220480010065
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Journal of the Society of Cosmetic Scientists of Korea
2022 Volume.48 No. 1 p.65 ~ p.70
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Anti-pigmentation Effects of Panax vietnamensis Extracts via Tyrosinase Expression
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Kim Young-Joo
Cha Hwa-Jun
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Abstract
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In this study, the anti-pigmentation efficacy of Panax vietnamensis (P. vietnamensis), a ginseng native to Vietnam, was confirmed. Melanin synthesis was repressed by ethanolic extracts of P. vietnamensis in B16F10 cells, melanocytes originated from mouse. At 250 μg/mL ethanolic extracts of P. vietnamensis, melanin contents were repressed by 64.04% compared to the control group. In addition, ethanolic extracts of P. vietnamensis downregulated tyrosinase activity and expression to 53.34% and 59.39%, respectively. As shown our result, ethanolic extracts of P. vietnamensis blocks α -MSH-mediated melanogenesis and is valuable whitening ingredients in cosmetics.
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KEYWORD
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Panax vietnamensis, melanin, pigmentation, tyrosinase
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